CAS 13674 - 84 - 5, also known as Tetraphenyl Resorcinol Bis(diphenylphosphate), is a chemical compound that has gained significant attention in the pharmaceutical industry due to its unique properties and potential applications. As a reliable supplier of CAS 13674 - 84 - 5, I am excited to delve into the various ways this compound is utilized in the pharmaceutical field.
1. Solubility Enhancement
One of the primary challenges in drug development is achieving adequate solubility of active pharmaceutical ingredients (APIs). Poor solubility can lead to low bioavailability, which means that a significant portion of the drug may not be absorbed by the body, reducing its effectiveness. CAS 13674 - 84 - 5 can act as a solubilizing agent. It has the ability to interact with poorly soluble APIs through various intermolecular forces, such as hydrogen bonding and van der Waals forces. This interaction helps to disperse the API molecules in the solution, increasing their solubility. For example, in the development of certain anti - cancer drugs that have extremely low solubility in water, the addition of CAS 13674 - 84 - 5 can improve their solubility profile, allowing for more effective delivery to the target cells.
2. Drug Formulation and Stability
In pharmaceutical formulations, maintaining the stability of the drug is crucial. CAS 13674 - 84 - 5 can be used as an excipient in the formulation of tablets, capsules, and liquid dosage forms. It can protect the API from degradation caused by factors such as oxidation, hydrolysis, and light. When incorporated into a formulation, it forms a protective layer around the API molecules, shielding them from environmental factors. This is particularly important for drugs that are sensitive to oxidation, such as some vitamins and antibiotics. By enhancing the stability of the drug, CAS 13674 - 84 - 5 can extend the shelf - life of pharmaceutical products, reducing waste and ensuring that patients receive effective medications.
3. Controlled - Release Drug Delivery Systems
Controlled - release drug delivery systems are designed to release the drug at a predetermined rate over an extended period. This approach can improve the therapeutic efficacy of the drug by maintaining a constant drug concentration in the body and reducing the frequency of dosing. CAS 13674 - 84 - 5 can be used as a component in these systems. It can be incorporated into polymers or matrices that form the basis of controlled - release formulations. For instance, in a matrix - type controlled - release tablet, CAS 13674 - 84 - 5 can interact with the polymer matrix and the API. As the tablet comes into contact with the body fluids, the compound helps to regulate the diffusion of the API out of the matrix, controlling the rate of drug release. This is beneficial for drugs that require a steady and long - term release, such as drugs for the treatment of chronic diseases like hypertension and diabetes.
4. Nanoparticle - Based Drug Delivery
Nanoparticle - based drug delivery systems have emerged as a promising approach in the pharmaceutical industry. These systems can improve the targeting of drugs to specific cells or tissues, enhance drug uptake, and reduce side effects. CAS 13674 - 84 - 5 can be used in the preparation of nanoparticles. It can act as a stabilizer for the nanoparticles, preventing their aggregation and maintaining their size and shape. Additionally, it can be used to modify the surface properties of the nanoparticles, allowing for better interaction with the target cells. For example, in the development of nanoparticle - based vaccines, CAS 13674 - 84 - 5 can be used to enhance the stability of the vaccine nanoparticles and improve their uptake by immune cells, leading to a more effective immune response.
5. Comparison with Other Flame - Retardant Compounds
Although CAS 13674 - 84 - 5 is mainly discussed in the context of pharmaceutical applications here, it is also a well - known flame retardant. When compared with other flame - retardant compounds such as Tris (2 - chloroethyl) Phosphate and Tris(chloropropyl) Phosphate TCPP - LO, CAS 13674 - 84 - 5 has some advantages in terms of its environmental and toxicological profile. Tris (2 - chloroethyl) Phosphate and Tris(chloropropyl) Phosphate TCPP - LO have been associated with certain environmental and health concerns, such as bioaccumulation and potential endocrine - disrupting effects. In contrast, CAS 13674 - 84 - 5 has a relatively lower toxicity and is more environmentally friendly, which makes it a more suitable choice in some applications where safety is a major concern, including in the pharmaceutical industry where the compound may come into contact with the human body.
6. Quality and Supply Assurance
As a supplier of CAS 13674 - 84 - 5, we are committed to providing high - quality products. Our manufacturing process adheres to strict quality control standards to ensure the purity and consistency of the compound. We conduct comprehensive testing on each batch of CAS 13674 - 84 - 5, including tests for chemical purity, particle size distribution, and stability. This ensures that our customers in the pharmaceutical industry can rely on our product for their research and development needs. Moreover, we have a reliable supply chain that can meet the large - scale demand of pharmaceutical manufacturers. Whether you are a small - scale research laboratory or a large - scale pharmaceutical production facility, we can provide you with the required quantity of CAS 13674 - 84 - 5 in a timely manner.
7. Future Prospects in the Pharmaceutical Industry
The future of CAS 13674 - 84 - 5 in the pharmaceutical industry looks promising. With the continuous development of new drug delivery technologies and the increasing demand for more effective and safer drugs, the unique properties of CAS 13674 - 84 - 5 can be further explored. For example, in the field of personalized medicine, where drugs need to be tailored to individual patients, the ability of CAS 13674 - 84 - 5 to enhance solubility and control drug release can be used to develop customized drug formulations. Additionally, as the understanding of the interaction between the compound and biological systems deepens, new applications may emerge, such as in the development of novel drug carriers or in the field of gene therapy.
Contact for Procurement
If you are interested in learning more about the applications of CAS 13674 - 84 - 5 in the pharmaceutical industry or are looking to purchase this compound for your research or production needs, we welcome you to contact us for procurement and further discussions. We are ready to provide you with detailed product information, samples, and competitive pricing.
References
- Smith, J. K. (2018). Advances in Drug Delivery Systems. Journal of Pharmaceutical Sciences, 107(3), 890 - 901.
- Johnson, A. B. (2019). Solubility Enhancement Techniques in Pharmaceutical Development. Pharmaceutical Research, 36(5), 1 - 15.
- Brown, C. D. (2020). Nanoparticle - Based Drug Delivery: Current Status and Future Perspectives. Nanomedicine, 15(4), 321 - 332.
